Extended Data Fig. 3: Integrin subtype inhibition assay with MCATS. | Nature Biomedical Engineering

Extended Data Fig. 3: Integrin subtype inhibition assay with MCATS.

From: Detection of cellular traction forces via the force-triggered Cas12a-mediated catalytic cleavage of a fluorogenic reporter strand

Extended Data Fig. 3

a) Scheme showing the workflow of how the integrin inhibition assay was performed with MCATS. b-c) MCATS results of HeLa cell traction forces inhibited by different integrin monoclonal antibodies. Error bars represent standard error of the mean from n = 4 (Ttol = 12pN, panel b) and n = 5 (Ttol = 56pN, panel c) independent experiments. Significance is calculated by paired two-tailed t-test.

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