Extended Data Fig. 1: The immunological effects in peripheral tissues from SerBut treatment in the EAE model from the experiment in Fig. 6. | Nature Biomedical Engineering

Extended Data Fig. 1: The immunological effects in peripheral tissues from SerBut treatment in the EAE model from the experiment in Fig. 6.

From: A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice

Extended Data Fig. 1

a,b, The percentage of MHC class II+% and geometric mean fluorescent intensity (gMFI) of CD11chi dendritic cells (a) or F4/80+CD11b+ macrophages (b) isolated from mesenteric LN. c, The percentage of Foxp3+ of CD4+ T cells in the spleen, spinal cord-draining LNs (SC-dLNs), or mesenteric LNs (mLNs). Data represent mean ± s.e.m. Statistical analyses were performed using Student’s t-test.

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