Fig. 6: ULM flow-speed and direction maps, and flow-speed profiles for an ex vivo porcine heart and a patient’s heart, all in short-axis view.
From: Transthoracic ultrasound localization microscopy of myocardial vasculature in patients
a,d, Flow-speed maps corresponding to the SR density maps in Figs. 2 and 3. b,c, SR flow-direction maps of the boxed regions in a and d. e,f, Flow-speed profiles at the positions indicated by the red lines in b and c, generated by speeds on segments averaged across 0.5 mm width along the vessels. g,h, Flow-speed distribution of MBs passing through red lines in b and c. Measurements are for biological replicates. Bin width, 200 µm; black line, median; box limits, 25th and 75th percentiles; whiskers, minimum and maximum data points excluding outliers. The mean ± s.d. of the speed from left to right in g: 27.24 ± 18.71, 60.46 ± 28.00, 34.47 ± 24.30; h: 24.41 ± 16.98, 56.26 ± 32.32, 24.07 ± 16.85. Unpaired Mann–Whitney two-sided U-test was used. e, f, g and h demonstrate that large vessels have higher flow speeds at the centre than at the side.
