Extended Data Fig. 1: Comparison of agility of animals wearing no device, SOMM, dual-color SOMM, and SOMM with unoptimized cable.
Quantification of animal agility from recordings of behavior in an arena of 40-cm side length. Naïve mice were fitted with the devices on the day 1 and their agility was tested for the agility for three consecutive days. One trial under each condition per animal and day, resulting in a total n = 36 trials. Trial duration: 10 minutes. Inter-trial break: 1 hour. Box center line, median; Box shoulders: 25th and 75th and percentile; whiskers, maximum and minimum. Data points indicate trials. a. Extracted motion trajectories for mice carrying different devices. First column: representative mouse in homecage with the baseplate only. Second column: representative mouse with baseplate and SOMM connected by the optimized cable. Third column: representative mouse with baseplate and dual-color SOMM connected by the optimized cable. Fourth column: representative mouse with baseplate and dual-color SOMM connected by the unoptimized cable (SOMM, unoptimized wire). b. Boxplot of distance traveled across the 4 modalities. N.S., not significant by one-way ANOVA. ***P = 2.21 ×10-11. c. Assessment of moving agility across 3 days through measuring distance traveled inside the arena, across 4 modalities. d. Boxplot of mean speed across the 4 modalities. N.S., not significant by one-way ANOVA. ***P = 2.21 ×10-11. e. Assessment of moving agility across 3 days through measuring mean speed inside the arena. Scale bar: 10 cm in a.
