Fig. 2: Quantifying transitions between cognitive topographies.

a, Transition cost (energy) between each pair of 123 cognitive topographies (‘states’) from NeuroSynth. Rows indicate source states; columns indicate target states. b, Same as a, but showing only a subset of 25 out of 123 NeuroSynth states for visualization purposes. Matrices are sorted by increasing cost across both rows and columns. c, Distributions of the cost to transition to each cognitive topography from every other cognitive topography. Box plot: centre line, median; box limits, upper and lower quartiles; whiskers, 1.5× interquartile range; points, outliers. d, Variability (s.d.) of transition energy is greater along the column dimension (target states) than along the row dimension (source states). This effect is also observed for the subset of 25 terms (Supplementary Fig. 1; ***P < 0.001). Box plot: centre line, median; box limits, upper and lower quartiles; whiskers, 1.5× interquartile range; points, outliers. e, Histogram of the difference in transition cost between reaching each state (averaging across all possible source states) and leaving each state (averaging across all possible target states). Positive values indicate greater cost to reach a state than to leave it, whereas negative values indicate the reverse. f, Word clouds show the NeuroSynth terms that are more difficult to reach than to leave, on average (red), or more difficult to leave than to reach, on average (blue). Word size reflects ranking. Source data are provided as a Source Data file.