Fig. 2: Acute stability of CCMs exposed to FUS-MB treatment.
a, High-resolution T2-weighted spin echo images displaying either CCMs before sonication (top row) or 24 h following sonication (bottom row). Circles denote targeted CCMs and insets display magnified views of the targeted CCMs. b, Targeted CCM volumes before sonication and 24 h following sonication on T2-weighted spin echo images with colour indicating applied PNP. CCM volume does not significantly demonstrate changes in volume following sonication. NS, not significant; P = 0.41; two-tailed Wilcoxon matched-pairs signed-rank test. c, High-resolution susceptibility-weighted images of the same mice in a, displaying either CCMs before sonication (top row) or 24 h following sonication (bottom row). d, Targeted CCM volumes before sonication and 24 h following sonication on susceptibility-weighted images with colour indicating applied PNP. CCM volume does not significantly demonstrate changes in bleeding following sonication. P = 0.34; two-tailed Wilcoxon matched-pairs signed-rank test.
