Extended Data Fig. 6: Quantitative analysis of metabolic imaging results obtained from oligodendroglioma patients. | Nature Biomedical Engineering

Extended Data Fig. 6: Quantitative analysis of metabolic imaging results obtained from oligodendroglioma patients.

From: Ultrafast J-resolved magnetic resonance spectroscopic imaging for high-resolution metabolic brain imaging

Extended Data Fig. 6

a, T1C, T1w and T2w FLAIR structural images obtained from grade II oligodendroglioma (tumour 1) and grade III oligodendroglioma (tumour 2) patients, along with the normal and tumour ROIs for regional analysis. b, Box plots of the concentrations of different metabolites in these two oligodendroglioma patients. Metabolite concentrations were shown in arbitrary units. Box plots are represented by median and interquartile range, with ±1.5 interquartile range as whiskers. Significantly elevated Cho (87.6%, P < 0.001) and Lac (107.5%, P < 0.001) levels were observed in grade III oligodendroglioma (n = 337) in comparison with grade II oligodendroglioma (n = 374). Unpaired two-tailed Student’s t-tests were performed. Abbreviations: T1C, T1-weighted contrast-enhanced; T1w, T1-weighted; T2w, T2-weighted; FLAIR, fluid attenuated inversion recovery; ROI: region of interest; NAA, N-acetyl aspartate; Cho, choline; Lac, lactate.

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