Fig. 1: Characterization of the bacterial consortium AUN. | Nature Biomedical Engineering

Fig. 1: Characterization of the bacterial consortium AUN.

From: Tumour-resident oncolytic bacteria trigger potent anticancer effects through selective intratumoural thrombosis and necrosis

Fig. 1

a, Comparative genomic analyses of A-gyo versus P. mirabilis (ca-PM) (left), ca-PM versus A-gyo (centre) and UN-gyo versus R. palustris (ca-RP) (right). b, Transmission electron microscopy images of ca-PM (left) (n = 3 independent experiments) and A-gyo (right) (n = 3 independent experiments). c, Photos of bacterial colonies of ca-PM (left) and A-gyo (right). d, Bacterial motility assay. Data are represented as the mean ± s.e.m.; n = 10 independent experiments. ***P = 0.001 by Student’s two-sided t-test. e, The statistics of differential expression genes of AUN and UN-gyo, based on the log10 of transcripts per million (TPM). The solid black line represents the line of equality (y = x), indicating identical expression levels between AUN and UN-gyo, while the dashed lines show boundaries for deviations from equality, representing fold-change thresholds. f, Heat map for the gene expression level of AUN and UN-gyo (left) and comparative gene expression of AUN/UN-gyo (right) based on the log10 of TPM. g, Minimum inhibitory concentration test of various antibiotics against AUN. Data are represented as mean ± s.e.m.; n = 3 independent experiments.

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