Fig. 1: ASA–PD. | Nature Biomedical Engineering

Fig. 1: ASA–PD.

From: Large-scale visualization of α-synuclein oligomers in Parkinson’s disease brain tissue

Fig. 1

a, ASA-PD is an imaging and analysis method for detecting protein aggregates in tissue down to nanoscale aggregates. b, The five main steps for imaging and analysis. Background suppression and enhanced imaging improve the signal-to-noise ratio such that aggregates can be detected and quantified in the analysis pipeline, including the spatial distributions relative to cell-specific markers. BG, background. Panels a and b created with BioRender.com.

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