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High-resolution brain–computer interface with electrode scalability and minimally invasive surgery

We developed a thin, flexible microelectrode array that can be slid through a small slit in the skull onto the brain surface. We showed that this minimally invasive system records and stimulates neural activity across broad cortical areas, demonstrating high-resolution brain–computer interfacing in animals and in human pilot studies.

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Fig. 1: Minimally invasive ‘cranial micro-slit’ electrode array insertion captures decodable, high-resolution brain activity.

References

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This is a summary of: Hettick, M. et al. Minimally invasive implantation of scalable high-density cortical microelectrode arrays for multimodal neural decoding and stimulation. Nat. Biomed. Eng. https://doi.org/10.1038/s41551-025-01501-w (2025).

B.I.R. and C.H.M. used ChatGPT and Gemini to help prepare their contribution to this Research Briefing.

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High-resolution brain–computer interface with electrode scalability and minimally invasive surgery. Nat. Biomed. Eng (2025). https://doi.org/10.1038/s41551-025-01502-9

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