Supplementary Figure 8: miR-105-reprogrammed NIH3T3 cells promote tumour growth. | Nature Cell Biology

Supplementary Figure 8: miR-105-reprogrammed NIH3T3 cells promote tumour growth.

From: Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells

Supplementary Figure 8

(a) Female NSG mice received mammary fat pad injection of 1 × 106 MDA-MB-231 cells mixed with 1 × 106 NIH3T3 cells stably expressing anti-miR-105 or control. Tumour volume was measured over the indicated time course (two-way ANOVA, n = 7 mice per condition). (b) Representative IHC images showing Ki67 staining and the overall percentage of tumour cells positive for human Ki67 (two-sided t-test, n = 7 mice per condition). Bar = 100 μm. For the entire figure, data are shown as mean ± SD; ***P < 0.001. Source data are shown in Supplementary Table 5.

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