Supplementary Figure 7: Differential gene expression analysis of embryonic and extra-embryonic compartments.
From: Sequential formation and resolution of multiple rosettes drive embryo remodelling after implantation
(a)Differential gene expression analysis heat maps between epiblast (EPI) and extra-embryonic ectoderm (ExE) in E5.25, E5.5 and E5.75 embryos. Representative gene ontology (G0) terms enriched in each tissue are shown on the right of each heat map. E5.25: sections 2-4 EPI, sections 6-8 ExE; E5.5: sections 2,4,5 EPI, sections 6-11 ExE; E5.75 sections 3-8 EPI, sections 9-19 ExE. n=1 E5.25, n=1 E5.5 and n=1 E5.75 embryos (b) Combined principal component analysis (PCA) for embryonic and extra-embryonic sections from E5.25-E5.75. Purple outline: E5.25-E5.5 EPI; Cyan outline: E5.25-E5.5 ExE; Dashed purple outline: E5.75 EPI; Dashed cyan outline: E5.75 ExE. n=1 E5.25, n=1 E5.5 and n=1 E5.75 embryos.
