Extended Data Fig. 5: Kinetics of loop formation for loops of different size.
From: A chromosome folding intermediate at the condensin-to-cohesin transition during telophase
Loops were grouped according to size: a, loops less than or equal to 125 kb, b, loops greater than 125 kb and less than or equal to 200 kb, c, loops greater than 200 kb and less than or equal to 325 kb, d, loops greater than 325 kb. For each panel, top row: log2(observed/expected) Hi-C data for experimental time course, middle row: log2(observed/expected) Hi-C data for simulated time course, bottom row: the difference between experimental and simulated Hi-C data. Kinetics of loop formation is similar for all loop sizes. Three independent experiments were performed with similar results.
