Extended Data Fig. 2: Xrp1 is required for activation of apoptosis in RPS23R67K/+.
From: Ribosomopathy-associated mutations cause proteotoxic stress that is alleviated by TOR inhibition
a, Imaginal disc of a RPS23R67K/+ larva expressing an RNAi transgene against Xrp1 in the anterior compartment (marked with anti-Ci). The number of Dcp1-positive cells is lower in the anterior than in the posterior compartment where Xrp1 activity is unaffected. Scale bars represent 50 µm. Genotypes for each figure panel are available in Supplementary Table 1. Experiments were repeated independently three times with similar results.
