Extended Data Fig. 9: Effect of the BETi on inflammatory ccRCC tumour.

a, b, Flow cytometric analysis of cells in primary tumours from the experiments shown in Fig. 7a–d. n = 5 mice/group. a, Representative gating strategy used for analysing primary tumours. The percentages of each fraction are indicated. b, Relative quantification of CD11b⁺ and F4/80⁺ cell populations compared to all living cells in primary tumours. Two-sided Student’s t test. c–e Flow cytometric analysis of cells in primary tumours of mice bearing JQ1-pretreated OS5K-3 cells. n = 6 mice/group. c, Experimental overview. d, e, Quantification of relative neutrophil (CD11b⁺ and Ly-6G⁺ cell) (d), and CD11b⁺ and F4/80⁺ cell populations (e) compared to all living cells in primary tumours. Two-sided Student’s t test. In all panels in this figure, the bars represent means ± S.D.

Source data