Extended Data Fig. 10: Transcriptional response after inhibition of CDK7 by THZ2.
From: Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma
a, Heat map for 104 of the 114 genes that are reported to be downregulated after THZ1 also show downregulation after THZ2 (compared to DMSO treatment; remaining ten genes were not in matrix after filtering). b, Violin plots showing changes in activity of direct CDK7 targets for MM074, MM087 and MM057. Violin plots display cell densities as shape (n=27,163).
