Extended Data Fig. 2: Unmixing of arterial and venous endothelial cells.
From: Endothelial struts enable the generation of large lumenized blood vessels de novo
a, Rescue of ephrinb2a morphants with efnb2a mRNA. Embryos were grouped by the level of rescue (near full, partial or no rescue) of the floor of the DA, indicated by the asterisks. (n = 71 embryos analysed in one experiment, n numbers per group indicated in graph). Images are representative of 5 embryos analysed by confocal microscopy per group. b, Representative images and quantification of the number of struts in embryos treated with the Notch inhibitor DAPT or injected with an ephnb2a MO. As a control, embryos were injected with a scrambled MO. (n = 14 embryos per condition). Data presented as the median values with the first and third quartiles; the whiskers represent the minimum and maximum. Images are representative of 5 embryos analysed by confocal microscopy per condition. Scale bars are defined in the figure.
