Extended data Fig. 5: EP4 is the primary E-type prostanoid receptor on IEC.

a, Micrographs of PI and caspase 3/7 activity probe stained, biopsy-derived colonic organoids from human volunteers treated as indicated. b, normalized counts (fpkm) of Ptger2 and Ptger4 from C57BL/6 mouse intestinal organoids subjected to RNA-Sequencing and normalized counts (log₂ TPM) from the indicated publicly available single-cell RNA sequencing dataset from the mouse small intestine.