Extended Data Fig. 4: PAGA trajectory inference on DE and VE lineages. | Nature Cell Biology

Extended Data Fig. 4: PAGA trajectory inference on DE and VE lineages.

From: Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics

Extended Data Fig. 4

(a-b) Partition-based graph abstraction (PAGA) of VE and DE FOXA2POS lineages. Similar to PCA, the PAGA trajectory inference highlights the position of InterVE in between the VE and DE lineages. AVE – anterior visceral endoderm, DE1- early definitive endoderm, DE2 – later definitive endoderm, EmVE – embryonic visceral endoderm, ExVE – extra-embryonic endoderm, InterVE – intermediate visceral endoderm.

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