Extended Data Fig. 3: Comparison of Ribo-lite and mRNA-seq data for mouse oocytes and early embryos. | Nature Cell Biology

Extended Data Fig. 3: Comparison of Ribo-lite and mRNA-seq data for mouse oocytes and early embryos.

From: Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development

Extended Data Fig. 3

(a) Heat maps showing the expression levels of stage-specific genes sorted by Ribo-lite data and the mapped mRNA-seq data (left). Heat maps showing the expression levels of stage-specific genes sorted by mRNA-seq data and the mapped Ribo-lite data (right). Results are from two independent experiments. (b) Heat maps showing the Spearman correlation values for Ribo-lite and mRNA-seq data. Results are from two independent experiments. (c) The UCSC browser views of Mos, Btg4, Cnot7, Cnot6l and Cpeb1 in mRNA-seq and Ribo-lite. Representative results are from two independent experiments. (d) Heat maps showing the mRNA and translatome levels of 15 known dormant RNAs and 3 protein known to be down-regulated upon meiotic resumption in oocytes from different datasets27,28,29.

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