Extended Data Fig. 4: scRNA-seq reveals cell type heterogeneity in salivary gland organoids.

a, Heatmap revealing the scaled expression of differentially expressed genes for each cluster defined in Fig. 3a. Top marker genes for cell types by scRNA-seq from hiSGs on Day 80. Row-normalized heat map of the top 10 markers over all cells. b, Dot plot expression matrix with selected genes for cluster annotation displayed on the x axis and cluster on the y axis. c, Feature plots for the expression of human salivary gland-related genes in hiSGs. a-c,Ten organoids were pooled for one scRNA-seq experiment.