Extended Data Fig. 6: SARS-CoV-2 infects salivary gland organoids. | Nature Cell Biology

Extended Data Fig. 6: SARS-CoV-2 infects salivary gland organoids.

From: Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication

Extended Data Fig. 6

a, Feature plots of RamDA-seq samples of hiSGs on Day 80. The key gene markers for the classification of cell in hiSG. Ten organoids were pooled for one scRNA-seq experiment. b, Violin plots of ACE2 and TMPRSS2 in hiSGs. ACE2 and TMPRSS2 expressing cells were detected in ductal cell cluster. c, Feature plots of ACE2 and TMPRSS2 in hiSGs. ACE2 and TMPRSS2-positive cells were detected in the ductal cll cluster. d, Immunofluorescence for ACE2 and TMPRSS2 in hiSGs. Images are representative of three independent samples showing similar results. Scale bars, 100 μm. e, Feature plots of SARS-CoV-2 entry factors in hiSGs.

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