Extended Data Fig. 5: Extended Data Related to Fig. 5. | Nature Cell Biology

Extended Data Fig. 5: Extended Data Related to Fig. 5.

From: Quantifying propagation of DNA methylation and hydroxymethylation with iDEMS

Extended Data Fig. 5

a) Barchart of heavy and light methylation in mESC EdU+ dsDNA. b) Barchart of heavy and light methylation in EdU+ dsDNA at 12 h post-replication. c) Barchart of heavy and light methylation in EdU+ ssDNA and parental ssDNA at 12 h post-replication. d) Barchart of heavy and light methylation in NIH3T3 EdU+ ssDNA. e) Barchart of heavy and light methylation in NIH3T3 parental ssDNA. f) Barchart of heavy and light hydroxymethylation in mESC genomic DNA after heavy media switch for one cell cycle (12 h). g) Barchart of heavy and light hydroxymethylation in NIH3T3 genomic DNA after heavy media switch for one cell cycle (20 h). h) Barchart of heavy and light hydroxymethylation in EdU+ ssDNA and parental ssDNA at 12 h post-replication. In a-h), data are presented as mean values +/− SD from three or four biological replicates as indicated. <LOD, below limit of detection. Numerical source data are provided.

Source data

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