Fig. 5: Both parental and newly replicated DNA strands accumulate new methylation and hydroxymethylation post-replication. | Nature Cell Biology

Fig. 5: Both parental and newly replicated DNA strands accumulate new methylation and hydroxymethylation post-replication.

From: Quantifying propagation of DNA methylation and hydroxymethylation with iDEMS

Fig. 5

a, Scheme of SILAC-iDEMS strategy in asynchronous mESCs. b, Bar chart of heavy and light methylation in EdU+ ssDNA. c, Bar chart of heavy and light methylation in parental ssDNA. d, Bar chart of heavy and light hydroxymethylation in EdU+ ssDNA. e, Bar chart of heavy and light hydroxymethylation in parental ssDNA. In b–e, data are presented as mean ± s.d. from three biological replicates. <LOD, below limit of detection. Numerical source data are provided.

Source data

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