Extended Data Fig. 5: UMAPs of key myogenic genes in mouse Pax7 ablation and single nucleus RNA sequencing. | Nature Cell Biology

Extended Data Fig. 5: UMAPs of key myogenic genes in mouse Pax7 ablation and single nucleus RNA sequencing.

From: Regenerating human skeletal muscle forms an emerging niche in vivo to support PAX7 cells

Extended Data Fig. 5

Related to Fig. 4. Shown are representative individual UMAPs from mdx-NSG mice including non-injured, 8 days post injury (dpi), non-injured Pax7-ablated, and Pax7-ablated 8dpi. Notable gene expression on populations include: Left. satellite cells (Pax7, Vcam1, Notch3, Cdh15), myocytes (Myod1, Itga7, Myh3, Ncam1), and Right. Type IIB myofibers (Myh4), Type IIX myofibers (Myh1), and Type IIB.3 myofibers (Actc1, Prkag3, Casq1, Itgb1bp2, Tmem38a).

Back to article page