Extended Data Fig. 2: Generation of combined mouse dataset.
From: Distinct pathways drive anterior hypoblast specification in the implanting human embryo
a, Uniform Manifold Approximation Projection (UMAP) of mouse scRNA-seq datasets colored by original publication. N = 16395 single cells. b, UMAP of mouse datasets colored by age. c, UMAP of mouse datasets colored by assigned cell type. d, UMAPs of mouse datasets colored by a gradient indicating gene expression for canonical markers of epiblast (EPI), primitive endoderm/visceral endoderm (PrE/VE), primitive streak, and trophectoderm/extraembryonic ectoderm (TE/ExE). e, Heatmap of average WikiPathways signaling pathway module score split by cell type and stage. Visualized value is calculated average scaled score from individual single-cell module scores. Gene names were converted from mmus to hgnc gene symbols for module scoring.
