Extended Data Fig. 3: Manipulation of blastocoel volume during gastrulation.
From: Competence for neural crest induction is controlled by hydrostatic pressure through Yap
a, Spread of data points indicating change in volume between control, inflation, and deflation at stage 10 (n = 11, 15, 10 embryos, respectively), 11 (n = 10, 11, 8 embryos, respectively), and 12 (n = 11, 10, 10 embryos, respectively). b, Quantifying snai2 and foxd3 expression levels by ISH after indicated treatment. Data represent mean, error bars are s.d. Statistical analysis was performed using two-sided Dunnett’s test (*P = 0.0106; a, ***P = 0.0001; b, ****P ≤ 0.0001; a and b, CI = 95%). nsnai2 = 22control, 25inflation, 22deflation, nfoxd3 = 22control, 14inflation, 10deflation embryos (b).
