Extended Data Fig. 6: The transition of putative enhancers during fertilization and ZGA. | Nature Cell Biology

Extended Data Fig. 6: The transition of putative enhancers during fertilization and ZGA.

From: Mapping putative enhancers in mouse oocytes and early embryos reveals TCF3/12 as key folliculogenesis regulators

Extended Data Fig. 6

a, Heatmap and bubble plot comparing distal H3K27ac signals and motif enrichment (-log10 p-value, hypergeometric test with Bonferroni correction, one-sided from HOMER57, Methods), respectively, at putative enhancers in FGO, one-cell, early two-cell, and late two-cell stage embryos. b, Scatter plots comparing allelic H3K27ac and Lamin B1 DamID signals22 in the one-cell, late two-cell, 8-cell embryos, and mESCs. M, maternal. P, paternal. Pearson correlations of each stage are also shown. c, Lamin B1 DamID and DamID-only control signal profiles in FGOs22 and GO-P10 for chromosome 1 (n=4 biological replicates).

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