Extended Data Fig. 2: H3K27ac, gene expression, and chromatin accessibility in mouse oocytes and early embryos.

a, The UCSC browser view and heatmaps showing H3K27ac signals and RNA expression at representative genes. Oocyte-, pre-implantation- and post-implantation-specific putative enhancers are shaded green, red, and blue, respectively. b, Heatmaps showing the stage-specific distal H3K27ac signals and the mapped chromatin accessibility signals. DHS, DNase I hypersensitive site. c, Line charts showing the cumulative distribution of the distances between promoters of active and inactive genes (top 5,000) and nearest distal H3K27ac sites (top 10,000).