Extended Data Fig. 5: VARS depletion does not induce an integrated stress response response or demonstrate a global defect in translation. | Nature Cell Biology

Extended Data Fig. 5: VARS depletion does not induce an integrated stress response response or demonstrate a global defect in translation.

From: Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma

Extended Data Fig. 5

a, Western blot corresponding to Fig. 5a, b. b, Western blot analyses of integrated stress response after VARS depletion. c Polysome profiles and translation efficiency of M395 RES control or depleted of VARS (fold mean ± SEM of n = 3 independent replicates, two-tailed unpaired t-test was performed).

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