Extended Data Fig. 5: Co-immunoprecipitation of prohibitins.

Co-immunoprecipitation of prohibitins from isolated mitochondria. Mitochondrial lysates from PHB-DK1 or PHB-DK2 knock-in cells were immunoprecipitated using Dreiklang as the bait protein. (a) Antibody detection; upper blot: PHB1, lower blot: PHB2. (b) Antibody detection; upper blot: ATP5A, lower blot: COX2. FT1: flow through of wildtype CoIP, FT2: flow through of PHB1-DK CoIP, FT3: flow through of PHB2-DK CoIP. 10 µg of sample was loaded for all samples of Input and flow through, respectively. Source blots are available.