Fig. 7: Cross-species analysis.
From: The guinea pig serves as an alternative model to study human preimplantation development
a, Integration of preimplantation scRNA data from 1,381 human and 541 guinea pig cells (derived from 98 human and 42 guinea pig embryos, respectively). b, Subspace projection illustrating the linkage between MNN pairs in human and guinea pig. Line colours indicate Pearson correlation coefficients. c, Alluvial plot comparing guinea pig developmental stages and lineages with human embryonic days and lineages among MNN pairs. d, Number of genes categorized in different groups. e–h, Heatmaps representing scaled pseudo-bulk expression of conserved genes within a lineage among species: human, guinea pig and mouse (e); human and guinea pig but not mouse (f); guinea pig and mouse but not human (g); human and mouse but not guinea pig (h). i, Line plot displaying the pseudo-bulk expression of selected transcription factors stratified by stages and lineages in human, guinea pig and mouse. Different species are represented by different colours.
