Extended Data Fig. 4: Structural comparison between murine and human NPCs.
From: Nuclear pores safeguard the integrity of the nuclear envelope
(a - c) Detailed architecture of the CR (a), NR (b), and IR (c) of the wild-type mES NPCs. The CR, NR, and IR models of the dilated human NPC (PDBID: 7R5J) are fitted into the corresponding cryo-EM maps. In (a) and (b), protomers at the center are highlighted with bold colors, while two adjacent protomers are indicated with pale colors. Note that Nup358 and Nup214 complex are CR-specific components. In (b), the position of the basket filament is highlighted with a green arrowhead. In (c), Nup155 molecules linking the IR with the CR or NR are colored in pale red.
