Fig. 5: Eight-fold symmetric NPCs in the Nup133−/− mES cells more frequently possess incomplete CR and NR architectures than wild-type mES NPCs. | Nature Cell Biology

Fig. 5: Eight-fold symmetric NPCs in the Nup133−/− mES cells more frequently possess incomplete CR and NR architectures than wild-type mES NPCs.

From: Nuclear pores safeguard the integrity of the nuclear envelope

Fig. 5

a, Representative results of TM analysis of an eight-fold symmetric NPC in Nup133−/− mES cells. b, 3D histogram showing the number of eight-fold symmetric Nup133−/− mES NPCs and their differing numbers of CR and NR peaks (n = 24 NPCs). c, Representative results of the TM analysis of an eight-fold symmetric NPC in wild-type mES cells. d, Analysis as in b for the eight-fold symmetric wild-type mES NPCs (n = 29 NPCs). In a and c, 3D plots of the peaks and pseudo-composite map are as in Fig. 4a. In the pseudo-composite map in a, a gap in the ring architecture is indicated with a red arrowhead. In b and d, bars that include the examples shown in a and c are indicated by green arrowheads.

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