Extended Data Fig. 6: Meningeal fibroblast cluster markers and proportions. | Nature Cell Biology

Extended Data Fig. 6: Meningeal fibroblast cluster markers and proportions.

From: Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth

Extended Data Fig. 6

a, Dot plot showing the top five differentially expressed genes by Log Fold Change (MAST test, LFC >0.25, minimum percent expression >0.1) in meningeal fibroblasts from LPT-WT and LPT-MET samples. b, Box plots showing the LMF1-LMF7 mean cluster fractions per sample from LPT-WT (n = 3 mice) and LPT-MET (n = 4 mice) scRNA-seq data. Center line represents median (50% percentile), hinges represent the 25% and 75% percentile, and whiskers represent the 1.5 interquartile range. P values were generated using two-tailed Student’s t-test.

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