Extended Data Fig. 5: Metabolic and lipidomic profile of mouse HSCs and progenitors. | Nature Cell Biology

Extended Data Fig. 5: Metabolic and lipidomic profile of mouse HSCs and progenitors.

From: Differentiation, ageing and leukaemia alter the metabolic profile of human bone marrow haematopoietic stem and progenitor cells

Extended Data Fig. 5

a, Representative FACS gating scheme of mouse HSCs (LSK CD150+ CD48-) and progenitors (LS-K). b, Heatmap of all detected metabolites passing quality thresholds in both mouse and human targeted metabolomics of HSCs/HSPCs and progenitors. The log2FC values between paired HSCs/HSPCs and progenitors per individual are depicted. n = 13 and 17 for mouse and human, respectively. (b) n indicates the number of biological replicates per condition.

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