Fig. 1: Membrane-bound organellophagy receptors. | Nature Cell Biology

Fig. 1: Membrane-bound organellophagy receptors.

From: The intrinsically disordered regions of organellophagy receptors are interchangeable and control organelle fragmentation, ER-phagy and mitophagy flux

Fig. 1

a, Schematics of the topology of ER-phagy receptors in mammalian (human, left) and yeast (S. cerevisiae, right) cells. RHD is shown in light blue, the blue rectangles show the conventional transmembrane domain, the green line shows the IDR and the LIR is shown in grey. b, Same as a for mitophagy receptors. IMS, intramembrane space. c, Same as a for mammalian Golgiphagy receptors. d, The length of IDR modules in amino acids. AA, amino acid. e, The net cumulative charge of cytoplasmic IDR modules at physiologic pH calculated using https://www.biosynth.com/peptide-calculator.

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