Extended Data Fig. 8: YAP recruits CTCF to mediate long-range chromatin interactions. | Nature Cell Biology

Extended Data Fig. 8: YAP recruits CTCF to mediate long-range chromatin interactions.

From: A subset of transposable elements as mechano-response enhancer elements in controlling human embryonic stem cell fate

Extended Data Fig. 8

a, Heatmaps showing CTCF occupancy at YAP/CTCF co-occupied peaks in WT and YAP-KO cells. b, c, Aggregate Peak Analysis (APA) plots (b) and box plot quantification (c) of chromatin interactions anchored at YAP/CTCF co-occupied peaks in WT and YAP-KO cells. Loss of YAP reduces these interactions. n = 2 biologically independent experiments. In box plots(c), center lines represent the median value, box limits the 25th and 75th percentiles, and whiskers denote minima and maxima (1.5× the interquartile range). Source numerical data are available in source data.

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