Extended Data Fig. 3: Dynamics of H3K4me3, H3K27me3, and RNA Pol II resetting during mouse peri-implantation embryonic development.
From: Remodelling bivalent chromatin is essential for mouse peri-implantation embryogenesis
a. Genome-wide occupancy dynamics of H3K4me3 and H3K27me3 during EPI and PE lineage segregation. b. Distribution of H3K4me3, H3K27me3 and bivalent domains across genomic regions in EPI and PE lineages during implantation. c. PCA of H3K4me3 (left) and H3K27me3 (right) profiles across EPI and PE lineages during peri-implantation development. d. The numbers of genes gain and lose H3K4me3, H3K27me3, or bivalent marks at different stages, calculated relative to the preceding stage. e. Dynamic changes in RNA Pol II signals around the TSSs of lineage-specific genes in ICM, EPI, and PrE/VE. Source numerical data are available in source data.
