Extended Data Fig. 7: Single-step photobleaching confirms detection of individual probes in cells. | Nature Chemistry

Extended Data Fig. 7: Single-step photobleaching confirms detection of individual probes in cells.

From: Single-molecule visualization of DNA G-quadruplex formation in live cells

Extended Data Fig. 7

a, 20 nM SiR-PyPDS binding to targets in a living cell. The red square indicates a single binding event. b, Intensity traces from three binding events in A, showing probes undergoing single-step photobleaching. The insets show time lapses for each molecule. Similar single-step photobleaching could be observed in all single-molecule video acquisitions.

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