Fig. 1: Malleicyprols, virulence factors encoded by conserved locus in BP group pathogens.
From: Pathogenic bacteria remodel central metabolic enzyme to build a cyclopropanol warhead
a, Gene cluster coding for malleicyprol biosynthesis. KARI, ketol-acid reductoisomerase b, Structures of malleicyprols 2 and 3 and their degradation product 1, and selected steps in the biosynthesis of the C5 building block. See Extended Data Fig. 1. for detailed biosynthetic pathway. c, Ring-opening of cyclopropanols mediated by single-electron oxidation.
