Extended Data Fig. 3: Transcript abundance and RT-stop frequencies are strongly concordant between RBRP sequencing libraries from two biological replicates. | Nature Chemistry

Extended Data Fig. 3: Transcript abundance and RT-stop frequencies are strongly concordant between RBRP sequencing libraries from two biological replicates.

From: Pervasive transcriptome interactions of protein-targeted drugs

Extended Data Fig. 3

a-c, Scatter plot showing very strong correlation of transcript expression value (RPKM) between two biological replicates (Pearson correlation r = 1.00) in HEK293 cells treated with Lev-AI only (a), Lev-AI and excess unmodified Lev (b), and DMSO (c). d-f, The concordance of RT-stop frequencies is high for most transcripts of read depth higher than the optimized cut-off value (200) in sequencing libraries of Lev-AI only (d), Lev-AI and excess unmodified Lev (e), and DMSO (f).

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