Fig. 2: Design, fragment combination and synthesis of spiroindolylindanone PNPs.
From: A divergent intermediate strategy yields biologically diverse pseudo-natural products
a, Indolenine and indanone fragment combination to construct spiroindolylindanone PNPs. b, Method development and optimization of a CO insertion reaction to construct spiroindolylindanone PNPs using N-formyl saccharin (2a) as a non-toxic bench-stable solid and inexpensive CO surrogate. c, Substrate scope for the spiroindolylindanone synthesis. aThe PNPs in this manuscript are identified by the letter of the compound class followed by the compound number within the compound class, that is, A1 is class A, compound 1. bIsolated yields are shown.
