Extended Data Fig. 8: Cryo-EM density features of SOI. | Nature Chemistry

Extended Data Fig. 8: Cryo-EM density features of SOI.

From: Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase

Extended Data Fig. 8

a, Isolated density map for four transmembrane (TM) helices and intracellular loops of SOI contoured at 12σ threshold level. b, Cryo-EM density features of nanobody contoured at 10σ levels. c-e, Cryo-EM density features of the haem b prosthetic group in the absence (panel c) and in the presence of the competitive inhibitor benzylamine (panel d), and density features of the benzylamine (panel e). f-h, Cryo-EM density features of overall SOI–NB complex showing densities features of ordered water molecules near the catalytic centre (panel g) and the SOI–NB interface (panel h).

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