Fig. 2: Structural organization of the SOI–NB complex. | Nature Chemistry

Fig. 2: Structural organization of the SOI–NB complex.

From: Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase

Fig. 2

a, Side view of the SOI–NB complex. b, One nanobody binds to the periplasmic loops of two adjacent protomers. Periplasmic loop 1 (PL1) of one subunit is shown in grey and periplasmic loop 2 (PL2) of a neighbouring SOI protomer is shown in blue. c,d, Details of the interaction between the SOI and nanobody. c, Interacting amino-acid residues of PL1 and PL2 are shown in white and cyan, respectively. The nanobody is shown as a space-filling model in orange. d, Interacting amino acids of NB-CDR1, NB-CDR2 and NB-CDR3 are labelled in yellow, brown and orange, respectively. e, The interaction between nanobodies is mediated by four residues that are conserved among nanobodies.

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