Fig. 4: Docking experiments explain the substrate range and regio-selectivity and stereo-specificity of SOI. | Nature Chemistry

Fig. 4: Docking experiments explain the substrate range and regio-selectivity and stereo-specificity of SOI.

From: Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase

Fig. 4

a, The substrate binding pocket occupied by benzylamine, as seen in the cryo-EM structure (left) and key interactions (right). b–e, Different substrates docked to the binding pocket. Left: (S)-styrene oxide (b), (R)-styrene oxide (c), (S)-α-methylstyrene oxide (SAMO) (d) and (1S,2S)-trans-2-methyl-3-phenyloxirane (MPO) (e). Right: key interactions.

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