Extended Data Fig. 4: Bioinformatic analysis of non-identified and whole proteome histidiens.
a) Histogram plot showing the distribution of distances of non-identified histidine sites to the active sites for the identified proteins. b) Calculation of the proportions of identified histidine sites, non-identified histidine sites, and histidine residues in the active site for the identified proteins, as well as the proportion of histidine residues in the active site for the human proteome. c) The distribution of solvent accessibility of non-identified histidine residues in the identified proteins. d) The distribution of solvent accessibility of histidine residues in human proteome. e) The secondary structures analysis of the distribution of non-identified histidine sites in the identified proteome. f) The secondary structures analysis of the distribution of histidine residues in human proteome.
