Extended Data Fig. 4: Characterization of binding and crosslinking activity of H3K9NleS+me2 peptide to MPP8.

a, 3D structure of H3K9me3 peptide and MPP8 (PDB: 3R93). b, High resolution mass spectrum of the reaction mixture of H3K9NleS+me2 peptide (5) and MPP8 under 20 min UV-B irradiation. c, Binding kinetics of interaction between MPP8 and H3K9NleS+me2 peptide (S16) by bio-layer interferometry.