Extended Data Fig. 6: Comparison of crosslinking activities by NleS+me2 peptide, NvaS+me2 peptide, and Met+me peptide.

The reader protein CBX1, BPTF and dSfmbt were applied to crosslinking by the sulfonium peptide with distinct side chain. The product yields were calculated based on the peak integrations from mass spectra as shown in Fig. 4e.