Extended Data Fig. 1: Gel-ABPP of alkyne stereoprobes in human cancer cells.
From: Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells
a, In situ reactivity of alkyne stereoprobes (5 µM, 1 h) in Ramos cells as determined by gel-ABPP. b, In vitro reactivity of probe set 1 (5 or 20 µM, 1 h) in Ramos and 22Rv1 cell lysate. Red asterisks mark examples of stereoselective stereoprobe-protein interactions. a, b, data are from a single experiment representative of at least two independent experiments.
